(A) Proposed mechanism of magnetic Au nanowreath and their applications as GSH-responsive imaging contrast agents. (B) In vivo MRI of tumors. (a–c) MR images of tumor-bearing mice and (d–f) corresponding quantificational signals analysis after injection of (a,d) magnevist, (b,e) ES-MIONs, and (c,f) magnetic AuNWs. (C) US, PAimaging, and merged tumor images at various time after injection of magnetic AuNWs upon illumination by an 808 nm laser. (D) Schematic illustration of self-assembly and ultrasound-GSH triggered disassembly of amphiphilic Janus Au-MnO vesicles. (E) Longitudinal relaxation rates and MR images (inset) of JNP Ve after GSH treatment. (F) NIR-II PAimaging signals and images (inset) of the JNP Ve. (G) Images of sections of cells with different treatment. (H) Diagram showing the mice model of orthotopic liver tumor. (I) In vivo MR images of mice obtained at 24 h post-injection of JNP Ve. (J) PAimaging of orthotopic liver tumor. (A-C) Reproduced with permission.[247] Copyright 2018, American Chemical Society. (D-J) Reproduced with permission.[186] Copyright 2020, WILEY-VCH.