The device independent segmentation performance of the proposed ONH-Net is shown. The segmentation performance on four randomly chosen (1-2 healthy; 3-4 glaucoma) Spectralis volumes from the test set are shown (one B-scan per volume). The 1st, 2nd, and 3rd columns represent the baseline, DL enhanced and the corresponding manual segmentation for the chosen B-scan. The 4th, 5th, and 6th columns represent the segmentations obtained when tested using the Spectralis, Cirrus, and RTVue trained segmentation model.