Figure 5. HMCN1 tracks in the tongue.

Tongue sections from mice at 3 months (A, D) and 2.5 days (B, C, E, F) of age were subjected to immunofluorescence assays (A-C) or hematoxylin & eosin staining (D-F). In WT adult tongue, HMCN1 was detected weakly along the epithelial BM and in the core of taste buds (A, D). In WT pup tongue, HMCN1 tracks were abundant in the core of taste buds and were additionally detected in the connective tissue (B, E). No HMCN1 was detected in Hmcn1^−/− pups (C, F). c, core; ct, connective tissue; m, muscle. Hmcn1 genotypes are designated in the upper right corner of each panel.