Table 3. Relationship between number of comorbidities and risk of death according to viral agent in pediatric patients with severe acute respiratory infection.
| Frequency | Crude model | Adjusted model* | ||||||
|---|---|---|---|---|---|---|---|---|
| Number of comorbidities | N | % | OR | 95% CI | p | OR | 95% CI | p |
| Influenza | ||||||||
| 0 | 477 | 72.4 | 1.00 | 1.00 | ||||
| 1 | 143 | 21.7 | 2.16 | 0.87-5.34 | 0.09 | 2.12 | 0.86-5.26 | 0.103 |
| ≥2 | 39 | 5.9 | 5.84 | 2.09-16.38 | 0.001 | 5.73 | 2.04-16.11 | 0.001 |
| Other respiratory virus | ||||||||
| 0 | 876 | 69.3 | 1.00 | 1.00 | ||||
| 1 | 300 | 23.7 | 2.47 | 1.33-4.56 | 0.004 | 2.51 | 1.35-4.69 | 0.004 |
| ≥2 | 88 | 6.9 | 2.65 | 1.06-6.64 | 0.038 | 2.71 | 1.06-6.96 | 0.037 |
| SARS-CoV-2 | ||||||||
| 0 | 1584 | 61.6 | 1.00 | 1.00 | ||||
| 1 | 707 | 27.5 | 3.01 | 2.32-3.91 | <0.001 | 3.03 | 2.34-3.94 | <0.001 |
| ≥2 | 279 | 10.9 | 4.76 | 3.45-6.56 | <0.001 | 4.81 | 3.48-6.63 | <0.001 |
Data represent closed cases entered into the National Epidemiological Surveillance Information System between January 1st and July 14th, 2020. Absence of information on a comorbidity was assumed to indicate absence of comorbidity.
*
Adjusted for sex and age.
ORV=other respiratory virus (respiratory syncytial virus, adenovirus, parainfluenza 1, parainfluenza 2, parainfluenza 3, parainfluenza 4, metapneumovirus, bocavirus, rhinovirus); OR=odds ratio; 95% CI=95% confidence interval.