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. 2020 Oct 9;142(22):2095–2106. doi: 10.1161/CIRCULATIONAHA.120.048792

Figure 4.

Figure 4.

Association between ECMELLA use and severe bleeding in prespecified subgroups. P interaction is 0.30 for age <52 years versus age 52 to 62 years, 0.11 for age <52 years versus age >62 years, and 0.50 for age 52 to 62 years versus age >62 years. P interaction is 0.21 for lactate <5 mmol/L versus 5 to 10.8 mmol/L, 0.77 for <5 mmol/L versus >10.8 mmol/L, and 0.32 for 5 to 10.8 mmol/L versus >10.8 mmol/L. P interaction is 0.74 for survival after venoarterial extracorporeal membrane oxygenation (SAVE) score >−6 versus −6 to −11, 0.72 for >−6 versus <−11, and 0.97 for −6 to −11 versus <−11. P interaction is 0.70 for Simplified Acute Physiology Score II (SAPS II) <52 versus −52 to 76, 0.67 for <52 versus >76, and 0.41 for 52 to 76 versus >76. AMI indicates acute myocardial infarction; CS, cardiogenic shock; ECMELLA, Impella+extracorporeal membrane oxygenation; eCPR, venoarterial extracorporeal membrane oxygenation–assisted cardiopulmonary resuscitation; OR, odds ratio; NS, nonsignificant; and VA-ECMO, venoarterial extracorporeal membrane oxygenation.