Skip to main content
. 2020 Nov 25;15(11):e0242806. doi: 10.1371/journal.pone.0242806

Table 1. Comparison of patient demographics, ACR TIRADS categories and CAD values according to the BRAFV600E mutation status.

BRAF + (n = 380) BRAF- (n = 89) P-value
Age (years) 43.1 ± 12.9 38.9 ± 11.8 .005
Sex .588
Female 288 (75.2) 65 (88.6)
Male 92 (24.8) 24 (11.4)
Tumor size (mm) 16 ± 7.3 20.8 ± 10.6 < .001
ACR TIRADS* < .001
2 1 (0.3) 4 (4.5)
3 6 (1.6) 11 (12.4)
4 65 (17.1) 12 (13.4)
5 308 (81) 62 (69.7)
CAD value 77.9 ± 21.8 60.9 ± 31.6 < .001

*Fisher’s exact test

Note—Age, tumor size, and CAD value are shown as means and standard deviations.

Categorical variables are shown as numbers of patients with percentages in parentheses.

BRAF+ = BRAFV600E mutation-positive, BRAF- = BRAFV600E mutation-negative

ACR TIRADS = the American College of Radiology Thyroid Imaging, Reporting and Data System

CAD value = risk of malignancy from CAD