Fig 2.

DdPCR KRAS mutation allele frequency (MAF; A), CEA (B), and CA19-9 (C) values of mCRC patients from baseline to the first sample collected with RECIST evaluation of five patients. Baseline values are shown at the zero day time point. Filled symbols indicate a RECIST evaluation of stable disease, while open symbols indicate a RECIST evaluation of partial response. Patient #10 is not shown in Fig 2C, as the CA19-9 levels for this patient were below the detection limit (<2 kU/L) at both baseline and at all follow-up time points.