Table 3. Clinicopathological correlation of pre-S deletion regions with HCC recurrence after surgery in 75 HBV-related HCC patients.
| Characteristicsa | Yes (No. of Patients (%)) | No (No. of Patients (%)) | P valueb |
|---|---|---|---|
| Pre-S1 del (nt 2854–2970) | 52 (100) | 23 (100) | |
| yes | 7 (13) | 3 (13) | 0.2858 |
| no | 45 (87) | 20 (87) | |
| Pre-S1 del (nt 2855–2872) | 52 (100) | 23 (100) | |
| yes | 4 (8) | 1 (4) | 0.3608 |
| no | 48 (92) | 22 (96) | |
| Pre-S2 del (nt 1–54) | 52 (100) | 23 (100) | |
| yes | 16 (31) | 1 (4) | 0.0080** |
| no | 36 (69) | 22 (96) | |
| Pre-S1+pre-S2 del (nt 2855–2872, 1–54) | 52 (100) | 23 (100) | |
| yes | 11 (21) | 1 (4) | 0.0532 |
| no | 41 (79) | 22 (96) |
aOnly patients with available data were analyzed.
bP value was determined by the chi-square test.
**, P value<0.01.
Abbreviations: HCC, hepatocellular carcinoma; HBV, hepatitis B virus; del, deletion; nt, nucleotide.