Table 2.

Distribution of variations in different genes. Total world Samples in June and October are 46,612 and 89,632, respectively. The VarFreq is the number of variations in the gene divided by the total number of samples. The relative frequency is the number of variations divided. Freq norm is the frequency divided by the total number of variations in each group. N/S is the ration between the number of non-synonymous and synonymous variations in the same gene.

Gene	Len	Var Count World June			Var Count World June			Var Count
M	669	464			515			2
N	908	1107			1371			23
E	228	266			320			1
ORF1ab	21,290	14,779			16,221			131
ORF3a	828	809			1003			6
ORF6	186	191			230			1
ORF7a	498	427			524			6
ORF8	193	366			439			4
S	3822	3405			3146			30
Gene	len	World June			World Oct.
Gene	len	RelativeFreq	RelFreqNorm	N/S	RelativeFreq	RelFreqNorm	N/S	RelativeFreq	RelFreqNorm	N/S
M	669	0.022	0.032	1.03	0.022	0.033	1.14	0.010	0.015	1
N	908	0.051	0.057	1.88	0.058	0.064	2.14	0.113	0.125	1.75
E	228	0.012	0.054	2.02	0.014	0.060	3.2	0.005	0.021	0
ORF1ab	21,290	0.686	0.032	1.24	0.692	0.032	1.25	0.645	0.030	1.48
ORF3a	828	0.038	0.045	2.38	0.043	0.052	2.5	0.030	0.036	4
ORF6	186	0.009	0.048	1.91	0.010	0.053	2.17	0.005	0.026	0
ORF7a	498	0.020	0.040	1.92	0.022	0.045	2.08	0.030	0.059	2
ORF8	193	0.017	0.088	1.9	0.019	0.097	1.88	0.020	0.102	3
S	3822	0.158	0.041	1.31	0.134	0.035	1.16	0.148	0.039	2