Table 2:
uninduced | nephrotic | |||
---|---|---|---|---|
nphs2Δipod*plg+/+ | nphs2Δipod*plg−/− | nphs2Δipod*plg+/+ | nphs2Δipod*plg−/− | |
venous pH | 7.28 ± 0.02 | 7.24 ± 0.01 | 7.31 ± 0.01 | 7.23 ± 0.02 * |
std HCO3−, mM | 22 ± 0.9 | 21 ± 0.8 | 25 ± 0.6 # | 22 ± 0.8 |
Na+, mM | 147 ± 0 | 150 ± 1 | 144 ± 1 # | 149 ± 2 * |
K+, mM | 4.1 ± 0.07 | 4.2 ± 0.13 | 4.9 ± 0.15 # | 5.1 ± 0.19 # |
Ca++, mM | 1.00 ± 0.01 | 1.13 ± 0.02 * | 1.03 ± 0.01 | 1.05 ± 0.04 |
Hct, % | 44 ± 1 | 44 ± 1 | 42 ± 1 | 42 ± 1 |
cHb, gdL−1 | 14.6 ± 0.3 | 14.4 ± 0.2 | 14.0 ± 0.5 | 13.8 ± 0.4 |
Arithmetic means ± SEM (n=8–11 each)
significant difference between uninduced and nephrotic mice of the same genotype,
significant difference between genotypes
Abbreviations: std standard, Hcthaematocrit, cHb calculated haemoglobin concentration