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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: FASEB J. 2020 Jul 5;34(8):10762–10777. doi: 10.1096/fj.202000702RR

Figure 1. Loxl1−/− demonstrate elevated IOPs.

Figure 1.

(A) IOPs was measured in age-matched mixed background littermates of Loxl1−/−, Loxl1+/− and Loxl1+/+ young (3 months, n=10 mice/20 eyes for both Loxl1−/− and Loxl1+/− mice, n=14 mice/28 eyes for Loxl1+/+ mice) and (B) older (8-12 month old mice (n=7 mice/14 eyes for Loxl1−/− mice, n=6 mice/12 eyes for Loxl1+/− mice and n=5 mice/10 eyes for Loxl1+/+ mice) using rebound tonometry under light anesthesia . IOPs were significantly higher in Loxl1−/− mice when compared to Loxl1+/+ mice at 3 and 8-12 months of age (*p<0.05). Data are shown as mean ± SD.