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. Author manuscript; available in PMC: 2021 Aug 1.

Published in final edited form as: FASEB J. 2020 Jun 23;34(8):10041–10055. doi: 10.1096/fj.202000215R

Table 1.

Daily study hemodynamic values.

	Day of study		P-value
	0	7	Interaction	Day	Group
Arterial pressure (mmHg)
Control	41.6 ± 0.5	43.9 ± 0.8	NS	0.029	NS
IGF-1	41.3 ± 3.3	42.3 ± 4.3	NS	0.029	NS
Venous pressure (mmHg)
Control	2.9 ± 0.6	2.7 ± 0.8	NS 0.061	NS	0.003
IGF-1	3.3 ± 1.1	4.3 ± 1.3	NS 0.061	NS	0.003
Heart rate (beats min⁻¹)
Control	173 ± 19	152 ± 13^†	0.002	-	-
IGF-1	175 ± 16	196 ± 25^*^†	0.002	-	-
Circumflex flow (mL min⁻¹)
Control	7.6 ± 4.0	8.3 ± 3.4	0.017	-	-
IGF-1	5.4 ± 1.4	18.9 ± 17.2^*^†	0.017	-	-
Circumflex flow (mL min⁻¹ g⁻¹)
Control	1.6 ± 0.8	1.5 ± 0.7	0.008	-	-
IGF-1	1.0 ± 0.2	2.7 ± 1.9^*^†	0.008	-	-

Control n=12; IGF-1-treated n=8. Data analyzed by 2-way repeated measures ANOVA.

^*

Different within-day from Control

^†

within-group from day 0 (P<0.05). Data shown as mean ± SD.