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. 2020 Nov 12;11:563030. doi: 10.3389/fmicb.2020.563030

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Copyright © 2020 Lu, Xu, Xia, Ma, Xu, Li and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Helical wheel diagram for AMPs. The helical wheel projection was generated using the online software HeliQuest (http://heliquest.ipmc.cnrs.fr). Hydrophobic amino acids on the non-polar face of the helix are colored in yellow, and hydrophilic amino acids on the polar face of the helix are colored in blue. The length of the downward-pointing arrow indicates the strength of hydrophobicity. (A) dh5; (B) dhvar4; (C) Pep05. A clearer interface between the polar and non-polar faces can be seen in Pep05 compared to dh5 and dhvar4.