TABLE 1.
Peptide | Sequence | Mass (Da) | <μ>1 | <H>2 | Net charge |
Histatin 5 | DSHAKRHHGYKRKFHEKHHSHRGY3 | 3,036 | 0.21 | −0.15 | + 5 |
Dh5 | KRKFHEKHHSHRGY | 1,847 | 0.20 | −0.17 | + 4 |
Dhar4 | KRLFKKLLFSLRKY | 1,840 | 0.59 | 0.38 | + 6 |
Pep05 | KRLFKKLLKYLRKF | 1,880 | 0.85 | 0.31 | + 7 |
1<μ> represents the mean amphipathic moment of helicalpeptides. 2<H> represents the mean hydrophobicity of helical peptides. 3Bold letters represent the putative active domain of histatin 5 (residues 11 to 24).