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Frequencies of SRE before and after the first 12 months of TKI treatment. Percentage and number of global SREs occurred after diagnosis of BM EGFR-mutated lung cancer before and after the first 12 months of TKI treatment, respectively (EGFR, epidermal growth factor receptor; SRE, skeletal related event; BM, bone metastases; TKI, tyrosine kinase inhibitor).
