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. 2020 Nov 12;11:566959. doi: 10.3389/fgene.2020.566959

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Copyright © 2020 Teng, Zhu, Zhang, Teng and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exploration of Differentially expressed (DE) lncRNAs and mRNAs in OP vs. NC and functional analyses. (A) Detection of the DE lncRNAs in volcano plot. Up-regulated lncRNAs (FC ≥ 2, P < 0.01) are labeled red, whereas down regulated lncRNAs (FC ≤ 0.5, P < 0.01) are labeled green. (B) Detection of the DE mRNAs in volcano plot. Up-regulated lncRNAs (FC ≥ 2, P < 0.01) are labeled red, whereas down regulated lncRNAs (FC ≤ 0.5, P < 0.01) are labeled green. (C) Heat map analysis of DE lncRNAs in OP vs. NC. The heat map was generated by hierarchical analysis of lncRNAs and samples. The heat map was generated by hierarchical analysis of lncRNAs and samples. (D) Heat map analysis of DE mRNAs in OP vs. NC. The heat map was generated by hierarchical analysis of mRNAs and samples. The red and blue represented up-regulated and down-regulated transcripts, respectively.