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. 2020 Nov 12;11:580572. doi: 10.3389/fneur.2020.580572

Table 1.

Background characteristics and proportion of atrial fibrillation detection.

Total
(N = 84)
MVO group
(N = 29)
Non-MVO group
(N = 55)
P-value
Age, mean (SD), years 68 (11) 67 (9) 68 (11) 0.54
Male sex, No. (%) 64 (76%) 21 (72%) 43 (78%) 0.56
CHADS2 score after stroke, median (IQR) 3 (3–4) 3 (3–4) 3 (3–4) 0.55
Congestive heart failure, No. (%) 5 (6%) 2 (7%) 3 (5%) 0.79
Hypertension, No. (%) 58 (69%) 19 (66%) 39 (71%) 0.61
Diabetes mellitus, No. (%) 17 (20%) 6 (21%) 11 (20%) 0.94
Large LADa, No. (%) (n = 81) 12 (15%) 4 (14%) 8 (15%) 0.92
High BNP or NT-proBNPb, No. (%) (n = 82) 17 (21%) 7 (24%) 10 (19%) 0.57
Frequent PACsc, No. (%) (n = 66) 16 (24%) 7 (29%) 9 (21%) 0.48
Endovascular thrombectomy, No (%) 17 (20%) 17 (60%)
Onset-to-implantation periodd, median (IQR), days 21 (14–39) 18 (14–32) 23 (13-41) 0.73
Whole follow-up periode, median (IQR), days 218 (158–345) 199 (156–353) 221 (157–332) 0.77
AF detection through ICM
   Within 90 days from ICM implantation, No (%) 19 (23%) 12 (41%) 7 (13%) <0.01
   During total follow-up period, No (%) 23 (27%) 13 (45%) 10 (18%) <0.01

AF, atrial fibrillation; BNP, B-type natriuretic peptide; ICM, insertable cardiac monitoring; IQR, interquartile rage; LAD, left atrial diameter; MVO, major vessel occlusion; NT-proBNP, N-terminal pro-B-type natriuretic peptide; and PAC, premature atrial contraction.

Differences between the MVO and non-MVO groups were evaluated using Fisher's exact test for PAF detection and other categorical variables and the Student t-test and Mann-Whitney U test for continuous variables.

a

Large LAD was defined as 45 mm or more.

b

High BNP or NT-proBNP was defined as >100 pg/mL or >300 pg/mL, respectively.

c

Frequent PAC was defined as the highest quartile of the patients enrolled in the current analysis, i.e., more than 222 beats a day.

d

Onset-to-implantation days were defined as days from index stroke onset to ICM implantation.

e

Whole follow-up period was defined as days from ICM implantation to the end of follow-up, i.e., until June 30, 2018.