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. 2020 Oct 22;22:1016–1024. doi: 10.1016/j.omtn.2020.10.019

Figure 1.

Figure 1

Overview of RNA-Seq and Rib-Seq in Cardiomyocytes Exposed Hypoxia

(A) Principal-component analysis (PCA) of transcriptome and translatome of each sample. PC1, PC2, and PC3 represent the top three dimensions that explain 35.8%, 18.2%, and 9.7% of the variance among all samples, respectively. (B) Heatmap of the global differentially expressed genes (DEGs). Gene expression values are standardized with Z score and the color represents the standardized values as shown in the color bar. NC, normoxia control; MH, mild hypoxia; SH, severe hypoxia.