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. 2020 Nov 12;8:589503. doi: 10.3389/fchem.2020.589503

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Copyright © 2020 Ribeiro, Rodrigues da Silva, Couto, Castro, Breitkreitz, Martinez, Igartúa, Prieto and de Paula.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of the hybrid NE formulation and its excipients by the FTIR-ATR (top) and DSC (down) techniques. The structural profiles of the alginate-sumatriptan complex (A,C) and nanoemulsions (B,D) were provided.