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(A) Tandospirone infusion into the anterior cingulate, in a dose-dependent manner, reduced self-grooming behavior in male+/− (HET) mice. (B) HET mice exhibited reduced line crossings compared with that of wildtype (WT) mice. Tandospirone did not affect line crossings in WT or HET mice. **P < .01 vs WT VEH, ++P < .01 vs HET VEH.
