TABLE 1.

The result of candidate biomarkers.

Metabolite	VIP	p-value	Fold Change(P/E)	RT (min)	SM
Linoleic acid (18:2)	6.328	0.009	1.68	13.26	–
Arachidonic acid (20:4)	4.590	0.015	2.20	15.72	–
Docosapentaenoic acid (DPA, 22:5)	3.434	0.038	2.28	22.06	–
Xanthosine	1.779	0.001	2.01	5.08	–
Palmitic acid (16:0)	2.962	0.028	1.72	23.35	–

RT, retention time; VIP, variable importance in projection; SM, scan mode; +, metabolites identified in the positive (ESI +) electrospray ionization mode; −, metabolites identified in the negative (ESI-) electrospray ionization mode. P/E, the probiotics group compared with the ethanol group.