Table 5.

Significantly over-represented canonical pathways among genes in modules unique to verbal and savant traits.

Ingenuity canonical pathways	–log(p-value)*	Ingenuity canonical pathways	–log(p-value)
(modules unique to verbal)		(modules unique to savant)
Axonal Guidance Signaling	11.1	NF-κB Signaling	4.49
Synaptogenesis Signaling Pathway	7.54	PI3K/AKT Signaling	2.68
Protein Kinase A Signaling	6.44	ERK/MAPK Signaling	2.40
Wnt/β-catenin Signaling	5.49	CREB Signaling in Neurons	2.14
p70S6K Signaling	5.42	PTEN Signaling	2.00
Reelin Signaling in Neurons	4.94	Protein Kinase A Signaling	1.98
Ephrin Receptor Signaling	4.91	Regulation of eIF4 and p70S6K Signaling	1.97
PTEN Signaling	4.67	p70S6K Signaling	1.88
EIF2 Signaling	4.19	Androgen Signaling	1.81
Neuregulin Signaling	4.14	mTOR Signaling	1.69

^*Negative logarithm of the Fisher Exact p-value which represents the probability that the pathway is not over-represented among the respective dataset of genes, where a value of 1.3 is equivalent to a p-value of 0.05.