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Expression of DDAH1 (A) and DDAH2 (B) mRNA in lung homogenates from wild-type and DDAH1−/− mice kept under normoxia or hypoxia for 4 weeks. mRNA expression was normalized to cyclophilin A (peptidylprolyl isomerase A, PPIA) as housekeeping gene, and to wild-type mice under normoxia as control group. Data are mean ± SEM of 5–7 animals per group. *p < 0.05 vs. normoxia; n.d., not detectable. NX, normoxia (21% O2); HX, hypoxia (10% O2).
