Table 7.

Some representative SPTB biomarker genes with the summaries of their functions.

Gene symbol	Gene name	Gene functions
ASRGL1	Asparaginase And Isoaspartyl Peptidase 1	$•$ Diseases associated with ASRGL1 include Telogen Effluvium and Masa Syndrome. Among its related pathways are Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism and Metabolism [60].
FADS2	Fatty Acid Desaturase 2	$•$ Diseases associated with FADS2 include Fanconi Anemia, Complementation Group D2 and Best Vitelliform Macular Dystrophy. Among its related pathways are alpha-linolenic acid (ALA) metabolism and fatty acid beta-oxidation (peroxisome) [61], [62], [63], [64].
GOLGA7	Golgin A7	$•$ GOLGA7 (Golgin A7) is a Protein Coding gene. Among its related pathways are Innate Immune System [65].
MCM2	Minichromosome Maintenance Complex Component 2	$•$ Diseases associated with MCM2 include Deafness, Autosomal Dominant 70 and Autosomal Dominant Non-Syndromic Sensorineural Deafness Type Dfna. Among its related pathways are E2F mediated regulation of DNA replication and Mitotic G1-G1/S phases [66], [67], [68], [69].
PLEC	Plectin	$•$ Diseases associated with PLEC include Epidermolysis Bullosa Simplex, Ogna Type and Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 17. Among its related pathways are Cell junction organization and Apoptotic cleavage of cellular proteins [70], [71], [72], [73].
VAMP2	Vesicle Associated Membrane Protein 2	$•$ Diseases associated with VAMP2 include Tetanus and Infant Botulism. Among its related pathways are Vesicle-mediated transport and Neurotransmitter Release Cycle [74], [75], [76].