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Effect of shikonin on microtubule cytoskeleton in SW620 colon cancer cells. SW620 cells were treated with vehicle (DMSO), 1.0 μM shikonin, paclitaxel, and vincristine for 48 h. Microtubules were stained with β-tubulin antibody and CoraLite488-conjugated anti-mouse IgG. Nuclear DNA was visualized by DAPI staining.
