Fig. 1.
A. The optimal ADAD cortical signature depicting cortical thickness differences between the ADAD and CNDIAN groups including age and sex as covariates and using a p < 0.001 cluster-wise threshold. The vertex-wise threshold was found to be p < 0.001 for right hemisphere and p < 0.0001 for left hemisphere. Significant vertices are depicted in yellow highlighting the inferior parietal and precuneus. B. The cortical thickness effect size maps comparing ADAD and CNDIAN. The blue indicates areas where the ADAD group had lower cortical thickness values compared to the CNDIAN and the red indicates areas where the ADAD group had higher cortical thickness values compared to the CNDIAN group. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)