Fig. 2.

Predicted favipiravir trough concentrations (C_trough), stratified on dosing and target.

A and B show individually predicted C_trough, stratified on dosing group (red dashed lines represent a putative C_trough target of 10 and 20 mg/L). C, D, E, F show individually predicted time above a target concentration of 10 mg/L (C, D) and 20 mg/L (E, F), stratified on dosing group. C, E show the results for the first two days of dosing, while D, F shows the results for the entire treatment duration. Dashed red lines represent a putative cut-off of >80% of time above the target, and solid black lines represent the median time above target C_trough within each group.