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. 2020 Nov 25;10:20572. doi: 10.1038/s41598-020-77556-3

Table 1.

Clinical characteristics after propensity score matching (NHIR database).

Variables Before matching After matching
Non-trauma group
(n = 122,924)
Trauma group
(n = 546)
p Value Non-trauma group
(n = 1,551)
Trauma group
(n = 517)
p Value
Gender (Male) 66,595 (54.2%) 421 (77.1%)  < 0.001 1183 (76.3%) 395 (76.4%) 0.952
Age (year) (IQR) 65.9 (53.7–74.5) 47.6 (29.0–64.3)  < 0.001 48.7 (34.2–64.9) 48.7 (31.5–65.3) 0.469
Pre-admission Comorbidities
Charlson comorbidity index (IQR) 0 (0–0) 0 (0–1)  < 0.001 0 (0–1) 0 (0–1) 0.075
Myocardial infarction 988 (0.8%) 3 (0.6%) 0.51 10 (0.6%) 3 (0.6%) 0.872
Congestive heart failure 5410 (4.4%) 22 (4.0%) 0.67 80 (5.1%) 22 (4.3%) 0.412
Cerebrovascular disease 9742 (7.9%) 13 (2.4%)  < 0.001 41 (2.6%) 13 (2.5%) 0.874
Dementia 1384 (1.1%) 1 (0.2%) 0.04 6 (0.4%) 1 (0.2%) 0.512
Chronic obstructive pulmonary disease 12,042 (9.8%) 30 (5.5%)  < 0.001 90 (5.8%) 30 (5.8%) 0.999
Peptic ulcer disease 12,025 (9.8%) 28 (5.1%)  < 0.001 99 (6.4%) 28 (5.4%) 0.428
Diabetes mellitus 42,643 (34.7%) 77 (14.1%)  < 0.001 209 (13.4%) 77 (14.9%) 0.419
Moderate or severe liver disease 7229 (5.9%) 24 (4.4%) 0.14 91 (5.8%) 24 (4.6%) 0.293
Chronic kidney disease 92,238 (75.0%) 130 (23.8%)  < 0.001 388 (24.9%) 130 (25.2%) 0.953
Advanced chronic kidney disease* 51,628 (42.0%) 41 (7.51%)  < 0.001 119 (7.6%) 41 (7.9%) 0.849
In-hospital Acute Comorbidities
Pulmonary complications
Prolonged mechanical ventilation** 10,506 (8.6%) 416 (76.2%)  < 0.001 1184 (76.0%) 387 (74.9%) 0.494
Re-intubation 5989 (4.9%) 228 (41.8%)  < 0.001 688 (44.2%) 217 (42.0%) 0.344
Acute respiratory distress syndrome 509 (0.4%) 7 (1.3%) 0.002 35 (2.3%) 7 (1.4%) 0.208
Pleural effusion 376 (0.3%) 3 (0.6%) 0.30 11 (0.7%) 3 (0.6%) 0.753
Chest tube insertion 1041 (0.9%) 111 (20.3%)  < 0.001 247 (15.9%) 90 (17.4%) 0.429
Hemodynamic complications
Hypovolemic shock 668 (0.5%) 12 (2.2%)  < 0.001 32 (2.1%) 10 (1.9%) 0.856
ECMO use 147 (0.1%) 17 (3.1%)  < 0.001 44 (2.8%) 12 (2.3%) 0.532
Main cause of infection
Pneumonia 2346 (1.9%) 5 (0.9%) 0.09 14 (0.9%) 5 (1.0%) 0.894
Urinary tract infection 2984 (2.4%) 4 (0.7%) 0.01 19 (1.2%) 4 (0.8%) 0.397
Severe sepsis 6041 (4.9%) 72 (13.2%)  < 0.001 243 (15.6%) 68 (13.2%) 0.166
Outcomes
Index hospital stay (day) (IQR) 6 (3–11) 15 (5–34)  < 0.001 12 (5–28) 15 (5–35) 0.007
Follow-up duration (year) (IQR) 3.32 (0.1–8.85) 2.49 ()
30-day mortality 2490 (2.0%) 99 (18.1%)  < 0.001 248 (15.9%) 95 (18.4%) 0.207
Long-term mortality 73,777 (60.0%) 134 (24.5%)  < 0.001 729 (46.8%) 129 (25.0%)  < 0.001
ESKD 32,445 (26.4%) 45 (8.2%)  < 0.001 208 (13.4%) 55 (10.6%) 0.892

ECMO, extracorporeal membrane oxygenation; ESKD, end stage kidney disease; IQR, interquartile range.

*Advanced chronic kidney disease: presence of CKD coding and concomitant reimbursement coding of erythropoiesis-stimulating agents without copayment.

**Prolonged mechanical ventilation: the use of mechanical ventilation ≥ 21 days.