Table 5.
Neonatal outcome
| Serial number | Author (reference) | Number of neonates | APGAR score (1 min, 5 min) | Neonatal symptoms (n) | Neonatal ICU admission (n) | Neonatal death | Neonatal RTPCR status |
| 1. | Alzamora M et al 78 | 1 | 6–8 | Respiratory difficulty Cough on D6 |
(1) (due to maternal sedation) | – | +ve |
| 2. | Chen H et al 45 | 9 | 8–10 | – | – | – | |
| 3. | Fan C et al 48 | 2 | 9–10 | Fever, abdominal distension, lymphopenia (1) Mild NNP, lymphopenia (1) |
– | – | Negative |
| 4. | Dong L et al 55 | 1 | 9–10 | – | – | – | |
| 5. | Zeng H et al 54 | 6 | 9–10 | – | – | ||
| 6. | Liu W et al 56 | 3 | 8–10 | Decreased responsiveness and decreased muscle tone | – | – | Negative |
| 7. | Zhu H et al 57 | 10 | 8–10 in all 7–8 in 1 |
Shortness of breath (6), vomiting (1), rash (1), fever (3) | Yes (2) | Yes (1) | Negative |
| 8. | Wang X et al 77 | 1 | 9–10 | – | Yes (1) | – | |
| 9. | Liu Y et al 69 | 10 | 10 | – | – | – | |
| 10. | Chen Y et al 58 | 4 | 8–9 (3) 7–8 (1) |
Oedema (1), rash (2), dyspnoea and TTN (1) | Yes (2) | – | Negative |
| 11. | Gidlöf S et al 76 | 2 | 9–10 | Breathing problem, cyanotic attack (1) | Negative | ||
| 12. | Huang J et al 86 | 1 | 8–9 | – | – | – | |
| 13. | Iqbal S et al 105 | 1 | 9 | – | – | – | |
| 14. | Lee D et al 80 | 1 | 9–10 | – | Yes (1) | – | |
| 15. | Khan S et al 85 | 3 | 9–10 | – | – | – | |
| 16. | Khan S et al 64 | 17 | 9–10 (16) 7–9 (1) |
NNP (5) | – | – | 2 out of 5 with pneumonia were +ve |
| 17. | Xiong S et al 50 | 1 | 9–10 | – | – | – | |
| 18. | Wang S et al 51 | 1 | 8–9 | Vomiting, lymphopenia, abnormal liver enzyme levels | Yes (1) | – | Negative |
| 19. | Zeng L et al 41 | 33 | Preterm newborn: 3, 4 Term: normal |
RD (4=3 ve, 1+ve). Cyanosis, feeding intolerance (3=2 ve,1+ve) Fever in 2, NNP in 3 of the 3+ve Lethargy, fever (1) lethargy, fever, NNP, leucocytosis, lymphocytopenia, vomiting (1) Preterm: neonatal RDS, NNP, lymphocytopenia (1) |
Yes (3) | – | +ve |
| 20. | Zamaniyan M et al 30 | 1 | 8, 9 | Fever (1) | – | – | +ve |
| 21. | Breslin N et al 59 | 18 | >7, >9 | RD/sepsis (1) | Yes (3) | – | Negative |
| 22. | Qiancheng X et al 107 | 23 | 10, 10 | – | – | ||
| 23. | Hantoushzadeh S et al 75 | 5 | 7 (2), 9–10 | NNP, lymphopenia (1) | Yes (1) | Yes (2) | Negative |
| 24. | Shanes E et al 36 | 15 | 7 (8), 8 (7); 9 | ||||
| 25. | Zambrano L et al 87 | 1 | – | – | Yes (1) | – | |
| 26. | Martínez-Perez O et al 65 | 82 | <5 (3) | RD (2) | Yes (19) | +ve | |
| 27. | Savasi V et al 109 | 57 | 10 | – | Yes (9) | – | |
| 28. | Song L et al 49 | 1 | 8, 9 | – | – | – | |
| 29. | Lokken E et al 40 | 8 | |||||
| 30. | Yan J et al 24 | 99 | 9, 10 | Neonatal asphyxia (1) | Yes (47) | Yes (1) | Negative |
| 31. | Pierce-Williams R et al 63 | 32 | 7.9±1.7 | – | Yes (21) | – | |
| 32. | Knight M et al 23 | 262 | Neonatal encephalopathy (1) | Yes (67) | Ys (2) | Unclear whether symptomatic neonate was +ve | |
| 33. | Kayem G et al 25 | 181 | – | Yes (37) | Yes (1) | ||
| 34. | Nayak A et al 26 | 131 | 7–10 (128) <7 (6) |
Neonatal seizures (1), MAS (1) | Yes (24) | Unclear whether symptomatic neonates were +ve | |
| 35. | Prabhu et al 60 | 73 | 9 | – | Yes (13) | – | Negative |
| 36. | Vivanti A et al 29 | 1 | 4,7 | Irritability, poor feeding, axial hypertonia and opisthotonos | Yes (1) | – | +ve |
| 37. | Li N et al 66 | 17 | 9.6±0.5, 10 | – | – | – | |
| 38. | Cao D et al 67 | 11 | 8–9, 10 | – | – | – | |
| 39. | Hu X et al 42 | 7 | 7–8, 8-9 | – | – | – | |
| 40. | Yang P et al 81 | 7 | 8–9,9-10 | Vomiting (1), RD (2), moaning (2) | Yes (5) | – | Negative |
| 41. | Yang H et al 73 | 13 | 9, 10 | Fever (1) | – | – | |
| 42. | Patane L et al 39 | 2 | 9, 10 | Mild feeding difficulty (2) | Yes (1) | – | +ve |
| 43. | Ferrazzi E et al 28 | 42 | <7 (2) | Gastrointestinal symptoms, RD (2) | Yes (3) | – | +ve |
| 44. | Govind A et al 61 | 9 | <7 (2) | NNP (1) | Yes (1) | – | +ve |
| 45. | Nie R et al 68 | 28 | 8–10, 10 | Pulmonary infection (1) | Yes (1) | – | +ve |
| 46. | Yin M et al 46 | 17 | 8, 9 | – | – | – | |
| 47. | Dória M et al 71 | 10 | 9, 10 | – | – | – | |
| 48. | Perrone S et al 72 | 4 | 9, 10 | – | – | – | |
| 49. | Romagano M et al 82 | 7 | 1–7, 4–9 | RD | Yes (7) | – | Negative |
| 50. | Cooke W et al 83 | 2 | 1–6, 3–8 | Bowel perforation D6 (1) | Yes (2) | – | Negative |
| 51. | Lowe B et al 62 | 1 | 9, 9 | – | – | – | |
| 52. | Blauvelt C et al 84 | 1 | 4, 8 | RD | Yes (1) | – | Negative |
| 53. | Kirtsman M et al 35 | 1 | 9,9 | Neutropenia, hypothermia, feeding difficulties, hypoglycaemic | Yes (1) | – | +ve |
| 54. | Lyra J et al 74 | 1 | 8, 9 | – | – | – | Negative |
| 55. | Groß R et al 52 | 2 | – | Respiratory symptoms (2), icterus (1) | – | – | +ve |
| 56. | Kulkarni et al 117 | 1 | 6, 9 | Fever, icterus and poor feeding | Yes (1) | – | +ve |
| 57. | Sisman J et al 70 | 1 | 7, 9 | Fever, RD, icterus | Yes (1) | – | +ve |
RD, Respiratory distress; MAS, Meconium aspiration syndrome; TTN, Transient Tachypnea of Newborn; NNP, Neonatal Pneumonia.