Table 3.
Total N = 134 |
Severe N = 19 |
Non-severe N = 115 |
P value | |
---|---|---|---|---|
Blood routine | ||||
Leukopenia | 43/134 (32.1%) | 11/19 (57.9%) | 32/115 (27.8%) | 0.009 |
Lymphopenia | 9/134 (6.7%) | 5/19 (26.3%) | 4/115 (3.5%) | 0.001 |
Neutropenia | 33/134 (24.6%) | 6/19 (31.6%) | 27/115 (23.5%) | 0.637 |
Blood biochemistry | ||||
ALT increased | 48/134 (35.8%) | 7/19 (36.8%) | 41/115 (35.7%) | 0.920 |
AST increased | 19/134 (14.2%) | 2/19 (10.5%) | 17/115 (14.8%) | 0.890 |
Total bilirubin increased | 3/134 (2.2%) | 0/19 | 3/115 (2.6%) | > 0.99 |
Albumin decreased | 7/134 (5.2%) | 4/19 (21.1%) | 3/115 (2.6%) | 0.005 |
Creatinine increased | 1/134 (0.7%) | 0/19 | 1/115 (0.9%) | > 0.99 |
CKMB increased | 15/134 (11.2%) | 1/19 (5.3%) | 14/115 (12.2%) | 0.622 |
LDH increased | 4/134 (3.0%) | 3/19 (15.8%) | 1/115 (0.9%) | 0.009 |
Troponin increased | 0/134 | 0/19 | 0/115 | |
Inflammation-related indicators | ||||
ESR increased | 63/97 (64.9%) | 15/16 (93.8%) | 48/81 (59.3%) | 0.008 |
CRP increased | 32/134 (23.9%) | 9/19 (47.4%) | 23/115 (20.0%) | 0.021 |
PCT increased | 3/127 (2.4%) | 0/19 | 3/108 (2.8%) | > 0.99 |
Coagulation function | ||||
D-dimer increased | 21/120 (17.5%) | 7/18 (38.9%) | 14/102 (13.7%) | 0.024 |
Chest CT findings | ||||
Normal | 61 (45.5%) | 2 (10.5%) | 59 (51.3%) | 0.001 |
Ground-glass opacity | 40 (29.9%) | 11 (57.9%) | 29 (25.2%) | 0.004 |
Local patchy shadowing | 13 (9.7%) | 1 (5.3%) | 12 (10.4%) | 0.774 |
Bilateral patchy shadowing | 25 (18.7%) | 11 (57.9%) | 14 (12.2%) | > 0.99 |
Interstitial abnormalities | 4 (3.0%) | 1 (5.3%) | 3 (2.6%) | 0.462 |
Fibrosis | 36 (26.9%) | 11 (57.9%) | 25 (21.7%) | 0.001 |
Bold values indicate that P value is less than 0.05
COVID-19 coronavirus disease 2019, ALT alanine aminotransferase, AST aspartate aminotransferase, CKMB creatine kinase isoenzyme, LDH lactate dehydrogenase, ESR erythrocyte sedimentation rate, CRP C-reactive protein, PCT procalcitonin