Table 4.

Multiple‐dose trial – serum troponin concentrations

	Placebo	Total danicamtiv
Troponin I (ng/mL, ULN = 0.03)	(n = 10)	(n = 30)
Median baseline	0.010	0.010
Median change from baseline (max change)	0.005 (0.03)	0.010 (0.87)
Median peak troponin post dose (max peak)	0.020 (0.05)	0.025 (0.88)
hs‐troponin T a (ng/mL, ULN = 0.014)	(n = 7)	(n = 22)
Median baseline	0.023	0.015
Median change from baseline (max change)	0.002 (0.005)	0.005 (0.041)
Median peak troponin post dose (max peak)	0.025 (0.032)	0.020 (0.052)

hs, high‐sensitivity; ULN, upper limit of normal.

^ahs‐troponin T assessment added after study had started.