Figure 1.

Metabolite profiles as presented by the radio chromatogram of [¹⁴C] levels after administration of an oral [¹⁴C]midazolam microtracer to children. The population was divided in four age groups/Hamilton pools: 0–1 month, 1–6 months, 6 months–2 years, and 2–6 years. [¹⁴C]levels were quantified with accelerator mass spectrometry. 1‐OHM, 1‐OH‐midazolam; 1‐OHMG, 1‐OH‐midazolam‐glucuronide. The corresponding high resolution mass spectrometry retention times can be found in Table  4 .