Table 1.
Demographics. Characteristics of the participants in this study
| Healthy kidneys | Kidney transplants | Healthy donors | RTRs pretransplantation | RTRs post‐transplantation | |
|---|---|---|---|---|---|
| n = 6 | n = 14 | n = 20 | n = 21 | n = 21 | |
| Sex, men (%) | 50% | 67% | 55% | 71% | 71% |
| Age in years, median [range] | 70.4 [57–78] | 48 [22–71] | 55.8 [37–71] | 60 [30–74] | 60 [30–74] |
| Diabetes mellitus (%) | Unknown | 28.6% | 0% | 38.1% | 47.6% |
| Original renal disease of the allograft recipient (%) | N/A | N/A | |||
| ‐FSGS | 21.4% | 4.8% | |||
| ‐Renovascular | 21.4% | 71.5% | |||
| ‐SLE | 14.3% | – | |||
| ‐IgAN | 7.1% | 4.8% | |||
| ‐ADPKD | 14.1% | 4.8% | |||
| ‐Polyarthritis nodosa | 7.1% | – | |||
| ‐Congenital anatomical abnormality | 7.1% | 4.8% | |||
| ‐Idiopathic membranous glomerulopathy | 7.1% | – | |||
| ‐Alport syndrome | – | 4.8% | |||
| ‐Unknown | – | 4.8% | |||
| Cause of transplant failure as reported in the medical file (%) | N/A | N/A | N/A | N/A | |
| ‐RUTI | 35.7% | ||||
| ‐Rejection | 42.8% | ||||
| ‐ATN | 14.3% | ||||
| ‐BK | 7.1% | ||||
| Months since renal transplantation, median [range] | N/A | 48 [0.3‐120] | N/A | N/A | 11.0 [8.0‐14.0] |
| Number of immunosuppressive agents at time of sample collection, median [range] | N/A | 1.5 [1‐4] | N/A | N/A | 3 [2‐3] |
ADPKD, autosomal dominant polycystic kidney disease; ATN, acute tubular necrosis; BK, polyomavirus BK‐induced nephropathy; FSGS, focal segmental glomerulosclerosis; IgAN, IgA nephropathy; N/A, not applicable; RTRs, renal transplant recipients; RUTI: recurrent urinary tract infection; SLE: systemic lupus erythematosus.