Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
LPS enhances the vulnerability to PTOA development. Healthy individuals exposed to systemic inflammation, like LPS, will develop symptoms similar to those of rheumatoid arthritis patients. In the joint, it will cause synovitis, which has an increase of macrophages type 1, eosinophils, neutrophils, and inflammatory cytokines and chemokines. An injury that happens at the time of elevated systemic inflammation will increase vulnerability and accelerate the development of PTOA.
