FIGURE 2.

A, Levels of PD‐1 mRNA in peripheral blood mononuclear cells (PBMCs) were similar among patients with ENKTL or DLBCL and healthy controls. B, Levels of PD‐L1 mRNA in PBMCs were significantly higher in ENKTL patients [2.23(1.16‐6.70)] and DLBCL patients [1.25(0.81‐1.99)] than in healthy controls [0.77(0.56‐0.96)]. Levels were also higher in ENKTL patients than in DLBCL patients. C‐G, In ENKTL patients, levels of PD‐L1 mRNA in PBMCs varied with C, Ann Arbor stage and level of lactate dehydrogenase (LDH), D, copy number of Epstein‐Barr virus genome, E, hemoglobin, F, lymphocyte count, and G, lymphocyte percentage. ****P < .0001, **P < .01. DLBCL, diffuse large B‐cell lymphoma; ENKTL, extranodal natural killer/T‐cell lymphoma