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. 2020 Jun 28;60(12):1585–1597. doi: 10.1002/jcph.1682

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© 2020 Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited. The Journal of Clinical Pharmacology published by Wiley Periodicals LLC on behalf of American College of Clinical Pharmacology

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Brentuximab vedotin mechanism of action. Figure reproduced from Suri A, Mould DR, Liu Y, Jang G, Venkatakrishnan K. Population PK and exposure‐response relationships for the antibody‐drug conjugate brentuximab vedotin in CTCL patients in the phase III ALCANZA study. Clin Pharmacol Ther. 2018;104(5)989‐999. ©2018 The Authors. Clinical Pharmacology & Therapeutics published by Wiley Periodicals, Inc. on behalf of the American Society for Clinical Pharmacology and Therapeutics. MMAE, monomethyl auristatin E.