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NanoDSF traces for the compounds showing the most significant KasA stabilization. (A) Ratio of mean fluorescence (350/330 nm). (B) Ratio of mean fluorescence 350/330 nm (1st derivative). KasA (10 μM) was tested in the presence of 100 μM of compounds. Sildenafil (purple) and triclosan (green) have a ΔTm of 6.7 and 3.8 °C, respectively.
