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. 2020 Nov 26;20:1805. doi: 10.1186/s12889-020-09923-8

Table 4.

Multivariate Cox Proportional Hazard Model Adjusted for Fibrinogen

Characteristics NHANES III 1988–1994 NHANES 1999–2002
Hazard Ratio 95% Confidence Interval P-value Hazard Ratio 95% Confidence Interval P-value
Fibrinogen (mg/dL) 1.001 1.000–1.002 0.07 1.00 0.998–1.002 0.75
Race/Ethnicity
 Whitea 1 1
 Black 1.26 0.98–1.63 0.07 1.30 0.74–2.27 0.35
 Hispanics/Other 0.89 0.60–1.32 0.56 1.27 0.62–2.58 0.50
Gender
 Malea 1 1
 Female 0.70 0.54–0.89 0.005 0.52 0.27–1.01 0.05
Education
 Below High Schoola 1 1
 High School/Equivalent 1.31 1.00–1.73 0.05 1.18 0.57–2.46 0.65
 Above High School 1.18 0.80–1.75 0.40 0.70 0.31–1.60 0.39
Income Level
 Lowa 1 1
 Middle 0.85 0.70–1.04 0.11 1.19 0.69–2.04 0.53
 High 0.78 0.55–1.11 0.16 1.52 0.76–3.04 0.23
Occupation
 Blue Collar, Semi-Routinea 1 1
 White Collar and Professional 0.89 0.59–1.32 0.55 0.75 0.43–1.31 0.30
 White Collar, Semi-Routine 0.93 0.60–1.45 0.75 1.10 0.62–1.94 0.73
 Blue Collar, High Skill 1.03 0.67–1.59 0.89 1.30 0.87–1.95 0.20
 Not Working 1.31 0.76–2.25 0.32 0.94 0.28–3.14 0.91
Body Mass Index (kg/m2)
 Underweighta 1 1
 Normal 1.36 0.71–2.59 0.35 1.84 0.37–9.25 0.44
 Overweight 1.08 0.60–1.94 0.80 2.07 0.45–9.51 0.34
 Obese 1.63 0.86–3.11 0.13 2.84 0.58–14.04 0.19
Smoking
 Nevera 1 1
 Former 1.69 1.16–2.45 0.01 2.24 1.32–3.80 0.004
 Current 3.87 2.87–5.23 < 0.001 7.17 4.23–12.16 < 0.001
Physical Activity
 About the Samea 1 1
 Less Active 1.15 0.85–1.55 0.35 1.19 0.60–2.35 0.61
 More Active 0.69 0.55–0.85 0.001 0.90 0.47–1.70 0.73

a Reference group

b Physical activity compared to others of same age