Table 3.

Risk factors for liver metastasis identified by univariate logistic regression analysis and multivariate logistic regression analysis

Characteristics	Univariate logistic regression analysis			Multivariate logistic regression analysis
	OR	95% CI	P	OR	95% CI	P
Age			0.336
≤ 65	1
> 65	0.890	0.701–1.129	0.336
Sex			< 0.001			0.015
Male	1			1
Female	0.631	0.498–0.800		0.723	0.557–0.939	0.015
Race			0.146
White	1
Black	1.194	0.892–1.599	0.233
Others	0.786	0.547–1.129	0.192
Marriage			0.254
Married	1
Unmarried	1.223	0.962–1.556	0.101
Unknown	1.156	0.680–1.965	0.593
Tumor location			< 0.001			0.057
Stomach	1			1
Duodenum	1.418	0.831–2.421	0.200	0.994	0.554–1.784	0.985
Jejunum	1.305	0.799–2.130	0.287	1.403	0.826–2.381	0.210
Ileum	0.399	0.124–1.286	0.124	0.377	0.110–1.293	0.121
Colon	1.947	0.929–4.079	0.078	0.686	0.312–1.511	0.350
Rectum	0.588	0.210–1.645	0.312	0.226	0.079–0.647	0.006
Others	3.069	2.198–4.285	< 0.001	1.043	0.708–1.537	0.831
Unknown	1.524	1.129–2.058	0.006	1.049	0.752–1.463	0.778
Tumor size			< 0.001			< 0.001
≤ 2 cm	1			1
2–5 cm	1.045	0.593–1.841	0.880	1.123	0.623–2.024	0.700
5–10 cm	1.790	1.052–3.045	0.032	1.584	0.910–2.755	0.104
> 10 cm	3.903	2.329–6.541	< 0.001	2.842	1.649–4.897	< 0.001
Unknown	10.493	6.048–18.026	< 0.001	4.251	2.359–7.660	< 0.001
N stage			< 0.001			< 0.001
N0	1			1
N1	6.046	3.932–9.296	< 0.001	3.313	2.057–5.337	< 0.001
Unknown	6.365	4.123–9.824	< 0.001	2.851	1.723–4.716	< 0.001
Mitotic rate			< 0.001			< 0.001
< 5/50 HPFs	1			1
≥ 5/50 HPFs	2.219	1.507–3.266	< 0.001	1.803	1.210–2.687	0.004
Unknown	7.615	5.599–10.365	< 0.001	5.763	4.091–8.116	< 0.001

OR odds ratio, 95% CI 95% confidence interval, HPFs high power fields