Table 1.
Epidemiological and clinical characteristics of patients on an intensive care unit in southwest Germany with and without extracorporeal membrane oxygenation (ECMO) treatment
| Characteristic | All patients (n = 105) | Patients on ECMO support (n = 30) | Patients without ECMO support (n = 75) | P |
|---|---|---|---|---|
| Epidemiology | ||||
| Male sex | 66 (62.9%) | 20 (66.7%) | 46 (61.3%) | 0.661 |
| Age (in years) | 57.3 ± 13.9 | 47.7 ± 13.1 | 61.2 ± 12.3 | < 0.001 |
| Body mass index (BMI) | 27.7 ± 8.3 | 28.8 ± 10.0 | 27.2 ± 7.5 | 0.482 |
| Clinical characteristics | ||||
| Sequential organ failure assessment (SOFA) score (average score and range) | 7.0 (4–9) | 7.4 (5–8) | 6.0 (4–9) | 0.340 |
| ICU mortality | 35 (33.3%) | 18 (60.0%) | 17 (22.7%) | < 0.001 |
| Median ICU stay until death (in days) | 23 (13–36) | 32 (22.5–50) | 14 (6.75–23.5) | 0.001 |
| Continuous renal replacement therapy (CRRT) | ||||
| Patients requiring CRRT | 40 (38.1%) | 16 (53.3%) | 24 (32.0) | 0.048 |
| CRRT blood flow (in ml/min) | 101.1 ± 19.6 | 100.6 ± 18.9 | 102.8 ± 25.9 | 0.411 |
| CRRT dialysate flow (in ml/h) | 2307.2 ± 536 | 2486.2 ± 541.6 | 2101 ± 470.7 | < 0.001 |
| ECMO characteristics | ||||
| Blood flow (in l/min) | 3.9 ± 1.1 | – | – | |
| Duration of ECMO membrane oxygenator use (days) | 12.6 ± 13.7 | – | – | |
Data were obtained during a study on therapeutic drug monitoring of antibiotics, October 2018–December 2019