Table 5.
Intermediate and cumulative systems effectiveness of delivery of ISTp-DP
| IST arm (N = 360)a | N | n | Intermediate process effectiveness, % (95% CI) | Cumulative delivery effectiveness, % |
|---|---|---|---|---|
| 1. 2nd or 3rd trimester women | 347 | 347 | 100 | 100 |
| 2. Given an RDT testb | 320 | 289 | 90.3 (70.7, 97.3) | 90.3 |
| 3a. RDT negative | 289 | 257 | 88.9 (84.3, 92.3) | 90.3 |
| 3b. RDT −ve not given any drug | 211 | 211 | 100 | 90.3 (3b = tested − ve) |
| 4a. RDT +ve | 289 | 32 | 11.1 (7.7, 15.7) | 90.3 |
| 4b. RDT+ ve given any DP | 32 | 29 | 90.6 (59.8, 98.4) | 81.8 |
| 5. DP given at correct dosec | 29 | 25 | 86.2 (56.5, 96.8) | 70.5 |
| 6. Given stat dose by DOT | 25 | 11 | 44.0 (15.0, 77.7) | 31.0 |
| 7. Correct no. tablets taken | 11 | 11 | 100 | 31.0 |
| 8. Health worker describe to woman how to take remaining doses | 11 | 2 | 0 | 5.6 |
| 9. Woman able to repeat instructions | 2 | 0 | 0 (9 = tested+ ve) | |
| 10. Composite endpoint | 347 | 211 | 60.8 |
aAnalysis limited to participants who were not given any antiretroviral and who did not report having a fever
b27 missing
cDP dose based on weight, stat dose given by DOT and remaining two doses given to take home—24 to 35.9 kg, 2 tablets; 36 to 74.9 kg, 3 tablets; > 75 kg, 4 tablets