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. 2020 Nov 25;19:245. doi: 10.1186/s12944-020-01419-z

Table 2.

Association between ALT/AST ratio and NAFLD in different models

Crude Model Model I Model II Model III Model IV
HRs (95%CI) aHRs (95%CI) aHRs (95%CI) aHRs (95%CI) aHRs (95%CI)
ALT/AST ratio 2.58 (2.44, 2.72) 2.61 (2.48, 2.76) 2.21 (1.97, 2.48) 2.11 (1.88, 2.36) 2.10 (1.88, 2.36)
ALT/AST ratio (Quintile)
 Quintile 1 Ref Ref Ref Ref Ref
 Quintile 2 2.00 (1.62, 2.47) 2.01 (1.63, 2.48) 1.66 (1.33, 2.08) 1.63 (1.30, 2.04) 1.63 (1.30, 2.04)
 Quintile 3 3.01 (2.47, 3.67) 3.04 (2.49, 3.72) 2.24 (1.82, 2.76) 2.06 (1.64, 2.60) 2.07 (1.65, 2.60)
 Quintile 4 4.82 (3.99, 5.81) 4.90 (4.07, 5.90) 2.99 (2.46, 3.65) 2.86 (2.33, 3.50) 2.84 (2.33, 3.48)
 Quintile 5 7.81 (6.52, 9.36) 7.97 (6.65, 9.55) 3.81 (3.14, 4.62) 3.51 (2.82, 4.37) 3.49 (2.78, 4.39)
P for trend < 0.001 < 0.001 < 0.001 < 0.001 < 0.001

Crude model adjusted for none

Model I adjusted for sex and age

Model II adjusted for sex, age, GGT, DBIL, TG, HDL-C and BMI

Model III adjusted for sex, age, ALP, GGT, GLB, TB, DBIL, BUN, CR, UA, FPG, TG, HDL-C, Height, BMI, SBP and DBP

Model IV adjusted for sex, age, GGT, ALB, GLB, TB, DBIL, SBP, DBP, ALP, BUN, CR, UA, FPG, TG, HDL-C, LDL-C, Height and BMI

Abbreviations: CI confidence interval, aHRs adjusted hazard ratios; other abbreviations as in Table 1