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. 2020 Nov 25;19:245. doi: 10.1186/s12944-020-01419-z

Table 4.

The result of the two-piecewise linear regression model

β (aHRs,95%CI) P-value
Total
 Fitting model by standard linear regression 0.74 2.09 (1.78, 2.46) < 0.001
 Fitting model by two-piecewise linear regression
 The inflection point of ALT/AST ratio 0.93
  ≤ 0.93 2.67 14.41 (8.91, 23.30) < 0.001
  > 0.93 0.01 1.01 (0.78, 1.30) 0.939
Male
 Fitting model by standard linear regression 0.71 2.02 (1.60, 2.56) < 0.001
 Fitting model by two-piecewise linear regression
 The inflection point of ALT/AST ratio 1.22
  ≤ 1.22 1.48 4.39 (2.97, 6.49) < 0.001
  > 1.22 −0.42 0.65 (0.37, 1.15) 0.143
Female
 Fitting model by standard linear regression 0.70 2.01 (1.60, 2.54) < 0.001
 Fitting model by two-piecewise linear regression
 The inflection point of ALT/AST ratio 0.89
  ≤0.89 3.47 32.01 (14.18, 72.25) < 0.001
  > 0.89 −0.19 0.83 (0.57, 1.21) 0.326

Adjust for: sex, age, GGT, ALB, GLB, TB, DBIL, SBP, DBP, ALP, BUN, CR, UA, FPG, TG, HDL-C, LDL-C, height and BMI