Table 2.

LncRNAs involved in osteoclast generation

lncRNAs	Species	Up/down	Overall impact	Targets	Steps impacted	References
LncRNA-Jak3	RAW264.7	Up	Positive	NFATc1	Osteoclast differentiation	[39]
LncRNA-LINC00311	Rat osteoclasts	ND	Positive	DLL3	Induces proliferation and inhibits apoptosis of osteoclasts	[40]
LncRNA-AK131850	Mouse osteoclasts	Up	Positive	miR-93-5p	Promotes vasculogenesis of endothelial progenitor cells	[41]
LncRNA-TUG1	BMMs	Up	Positive	ND	Promotes the proliferation and inhibits the apoptosis of osteoclasts	[42]
LncRNA-AK077216	RAW264.7; BMMs	Up	Positive	NFATc1	Promotes osteoclast differentiation and enhances osteoclast bone resorption	[43]
LncRNA-CRNDE	Human osteoclasts	Up	Positive	ND	Promotes osteoclast proliferation	[44]
LncRNA- DANCR	hOCPs; RAW264.7	Up	Positive	FOXO1	Promotes osteoclastic differentiation	[45]
LncRNA RP11-498C9.17	PBMs	Down	ND	ND	Controls osteoclastogenesis.	[46]
LncRNA -MIRG	RAW264.7	Up	Positive	miR-1897	Promotes osteoclastic differentiation	[47]