Table 2.
Changes of antibiotic prescribing behaviors in the case study hospital (thousand)
| Before (n = 728) | After (n = 721) | χ2 | p-value | |
|---|---|---|---|---|
| Total antibiotic prescription (ratea) | 145 (19.9) | 128 (17.8) | 1015 | < 0.001 |
| IV antibiotic prescription (rateb) | 62 (8.6) | 34 (4.7) | 8473 | < 0.001 |
| Oral antibiotic prescription (ratec) | 84 (11.6) | 95 (13.2) | 844.3 | < 0.001 |
| (n = 145) | (n = 128) | |||
| Classified antibiotic use rate d | ||||
| Non-restricted | 94 (65.4) | 90 (70.1) | 706.1 | < 0.001 |
| Restricted | 57 (39.8) | 41 (32.5) | 1558 | < 0.001 |
| Special | 3 (2.4) | 0.1 (0.1) | 2655 | < 0.001 |
| Antibiotic combination therapy e | 25 (17.7) | 14 (11.3) | 2231 | < 0.001 |
aTotal antibiotic prescription rate = the number of antibiotic prescriptions/total number of prescriptions;
bIV antibiotic prescription rate = the number of IV antibiotic prescriptions/total number of prescriptions;
cOral antibiotic prescription rate = the number of oral antibiotic prescriptions/total number of prescriptions;
dClassified antibiotic use rate = the number of classified-grade antibiotic prescriptions/total number of antibiotic prescriptions;
eAntibiotic combination therapy = the number of prescriptions with two or more antibiotic/total number of antibiotic prescriptions