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DLT by Dose Level
| Dose Level | Evaluable patients (n) | No. patients with DLT | DLT |
|---|---|---|---|
| 32 mg/m2/d | 3 | 0 | |
| 52 mg/m2/d | 3 | 0 | |
| 88 mg/m2/d | 8 | 2 | Prolonged neutropenia (n = 1) Prolonged thrombocytopenia (n = 1) |
| 116 mg/m2/d | 12 | 2 | Hemolysis (Gr 3), thrombocytopenia (Gr 4) (n = 1) Thrombocytopenia, Gr 4 (n=l) |
