Table 5:

Long Term Tolerability of Lenalidomide

Patient #	Dose level (mg/m2/d)	Total # cycles	Cycle at reduction	Reason for reduction
1	32	3
2	32	5
3	32	11
4	52	6	C4	Prolonged neutropenia
5	52	9
6	52	5
7	88	1
8	88	1
9	88	2
19	88	5	C4, C6	Gr 3 thrombocytopenia, Gr 4 neutropenia
23	88	7	C3, C5	Gr 4 neutropenia, Dose-limiting thrombocytopenia
26	88	7	C4, C6	Prolonged neutropenia
27	88	7	C4	Prolonged thrombocytopenia
28	88	4
29	88	13
10	116	5
11	116	1
13	116	41
14	116	7
15	116	1
16	116	6	C5	Gr 4 neutropenia
17	116	21
18	116	6
20	116	8
21	116	5	C5	Delay secondary to neutropenia Gr 3
22	116	23	C3, C5	Gr 4 neutropenia
24	116	5	C4	thrombocytopenia
25	116	7