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Comparison of papers regarding eye plaque brachytherapy used to treat large size tumors to COMS trials
| Trial | Study | n | Time | Local recurrence | Metastasis mortality | Overall survival |
|---|---|---|---|---|---|---|
| COMS medium | 125I plaque vs. enucleation | 1,317 | 5 years | 10.3% | 9% | 81% |
| 12 years | – | 21% | 57% | |||
| COMS large | EBRT before enucleation vs. enucleation alone | 1,003 | 5 years | N/A | 28% | 57% |
| 10 years | N/A | 60% | 40% | |||
| Shields et al. | 125I, 106Ru, 60Co, 192Ir | 354 | 5 years | 9% | 30% | – |
| 10 years | 13% | 55% | – | |||
| Puusaari et al. | 125I | 121 | 5 years | 6% | 35% | 62% |
