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Tumor cell EMT is driven by MMP10. (A) AMC-PDAC-053M cells were treated with NPS, HPS, and HPS + GM6001 under hypoxia. Scale bar: 20 µm. (B) Expression of VIM in cells were assessed by flow cytometry on PANC-1, AMC-PDAC-053M and AMC-PDAC-067. Data were normalized to NPS group and is shown by average gMFI ± S.E.M. (* p < 0.05, ** p < 0.01). A dot refers to a cell line.
