Table A3.
Genes of KEGG hypoxia pathway, activated stroma and normal stroma.
| KEGG Hypoxia | Activated Stroma | Normal Stroma | ||||||
|---|---|---|---|---|---|---|---|---|
| AKT1 | EPO | PDHB | COL1A1 | PLAU | THY1 | DES | CCDC3 | PLP1 |
| AKT2 | ERBB2 | PDK1 | COL10A1 | LOXL1 | GFPT2 | ACTG2 | SPON1 | ADH1A |
| AKT3 | FLT1 | PFKFB3 | SULF1 | COL5A1 | SMOC2 | MYH11 | APOLD1 | CAV1 |
| ALDOA | GAPDH | PFKL | COL3A1 | FBN1 | CD163 | CNN1 | SPEG | VIT |
| ANGPT1 | HIF1A | PGK1 | CTHRC1 | COL4A2 | RGS1 | SCRG1 | PTGDS | GPM6B |
| ANGPT2 | HK1 | PIK3CA | COL1A2 | CILP | AIF1 | SMOC2 | A2M | FMO2 |
| ANGPT4 | HK2 | PIK3CB | SFRP4 | CTGF | PLAT | ATP1A2 | CPE | C1S |
| ARNT | HK3 | PIK3CD | SPARC | TYROBP | TNFAIP6 | SPARCL1 | AQP1 | CSRP2 |
| BCL2 | HKDC1 | PIK3R1 | COMP | C20orf103 | HLA-DRA | SYNM | RCAN2 | SFRP1 |
| CAMK2A | HMOX1 | PIK3R2 | INHBA | CD248 | TIMP1 | C10orf116 | PTX3 | KCNMB4 |
| CAMK2B | IFNG | PIK3R3 | FAP | MXRA5 | CNN1 | MYLK | RSPO3 | PPAP2A |
| CAMK2D | IFNGR1 | PLCG1 | MMP11 | ACTA2 | LZTS1 | WISP2 | FABP4 | PMP22 |
| CAMK2G | IFNGR2 | PLCG2 | COL11A1 | ASPN | IFI30 | ANGPTL7 | CPXM2 | LPL |
| CDKN1A | IGF1 | PRKCA | THBS2 | COL8A2 | NID2 | MGP | NR4A1 | DUSP1 |
| CDKN1B | IGF1R | PRKCB | SFRP2 | IGFBP7 | FSTL1 | IGF1 | CLDN5 | STON1 |
| CREBBP | IL6 | PRKCG | LUM | PDGFRB | PPAPDC1A | TAGLN | CXCL12 | DSTN |
| CUL2 | IL6R | RBX1 | POSTN | COL16A1 | ACP5 | CFD | COX7A1 | GSN |
| CYBB | INS | RELA | FNDC1 | C1S | F13A1 | SOD3 | OGN | CCL19 |
| EDN1 | INSR | RPS6 | CTSK | COL8A1 | MGP | ACTA2 | MYL9 | PDGFRL |
| EGF | LDHA | RPS6KB1 | CCL18 | COL5A2 | ITGBL1 | AOC3 | MYOC | PLA2G2A |
| EGFR | LTBR | RPS6KB2 | SPON2 | MMP9 | CYR61 | MFAP4 | SGCA | ADH1C |
| EGLN1 | MAP2K1 | SERPINE1 | SPP1 | THBS4 | PLA2G7 | C2orf40 | ADAMTS1 | THBS4 |
| EGLN2 | MAP2K2 | SLC2A1 | ISLR | COL12A1 | NCF2 | LMOD1 | ID4 | GNG11 |
| EGLN3 | MAPK1 | STAT3 | FN1 | CSF1R | LOXL2 | LHFP | CRYAB | SLN |
| EIF4E | MAPK3 | TEK | DCN | EGR2 | IL4I1 | LOC387763 | C7 | FSTL1 |
| EIF4E1B | MKNK1 | TF | VCAN | ITGA11 | RAB31 | VWF | CILP | LGI4 |
| EIF4E2 | MKNK2 | TFRC | IGH | LOC387763 | LGALS1 | CLEC3B | RERGL | GPX3 |
| EIF4EBP1 | MTOR | TIPM1 | SPON1 | HTRA1 | VSIG4 | ITGA7 | PPP1R14A | MUSTN1 |
| ELOB | NFKB1 | TLR4 | MMP7 | VIM | NOX4 | GPIHBP1 | TPM2 | S100B |
| ELOC | NOS2 | VEGFA | CDH11 | HLA-DPB1 | ALOX5AP | HBB | CRLF1 | RPS4Y1 |
| ENO1 | NOS3 | VHL | MFAP5 | NNMT | CXCR4 | EFEMP1 | HSPB2 | ABCA8 |
| ENO2 | NPPA | GREM1 | HTRA3 | AEBP1 | RBP7 | PLN | IL33 | |
| ENO3 | PDHA1 | ZNF469 | TMEM204 | SRPX | NEXN | |||
| EP300 | PDHA2 | FCGR3A | FMOD | DCN | FMOD | |||